The Effect of Geoclimatic Factors on the Distribution of Paracoccidioidomycosis in Mato Grosso do Sul, Brazil.

The incidence of paracoccidioidomycosis (PCM) varies in Latin America, and it is influenced by environmental factors. This study evaluated the distribution of PCM acute/subacute form (AF) cases and their correlation with geoclimatic factors in the Mato Grosso do Sul (MS) state. The study included 81 patients diagnosed with the PCM/AF at the University Hospital of the Federal University of Mato Grosso do Sul between January 1980 and February 2022. Geographic coordinates, health microregion of patient's residence, compensated average temperature, relative air humidity (RH), El Niño Southern Oscillation (ENSO), and average global temperature were analyzed. The highest incidence was observed in the Aquidauana (7/100,000 inhabitants), while Campo Grande, the state's capital, had the highest number (n = 34; 42.4%) and density (4.4 cases/km2) of cases. The number of cases increased during extended periods of the El Niño phenomenon. A positive correlation was found between higher RH and PCM/AF cases. Most PCM/AF cases were found in areas with loamy soils and RH ranging from 60.8 to 73.6%. In MS, the health microregions of PCM/AF patients are characterized by deforestation for agricultural and pasture use, coupled with loamy soils and specific climatic phenomena leading to higher soil humidity.

HIV pre-exposure prophylaxis and incidence of sexually transmitted infections in Brazil, 2018 to 2022: An ecological study of PrEP administration, syphilis, and socioeconomic indicators.

BACKGROUND: Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is one of the pillars of a combination prevention strategy for reducing the risk of new infections caused by HIV. The daily use of antiretroviral drugs by individuals who are not infected with HIV is required to prevent infection. Although its efficacy has been well established in the literature, in recent years, the decreased supply of antiretroviral drugs has been associated with an increase in the incidence of sexually transmitted infections (STI) and changes in the social determinants of health. An ecological study was conducted covering a five-year period (2018-2022), starting from the year of initiation of PrEP administration in Brazilian state capitals. PRINCIPAL FINDINGS: Descriptive analysis was performed, and the spatial distribution of study data was taken into account. Correlation analysis was used to assess the association between PrEP administration, the incidence and detection rate of STI, and socioeconomic data. The southern region showed the highest incidence rates of STI, but the northern and northeastern regions demonstrated the worst socioeconomic indicators, especially those related to illiteracy and basic sanitation. PrEP administration was significantly correlated with illiteracy (ρ = -0.658), per capita income (ρ = 0.622), public garbage collection (ρ = 0.612), syphilis (ρ = 0.628) and viral hepatitis (ρ = 0.419) incidences. Further, all STI were significantly associated with illiteracy and per capita income. SIGNIFICANCE: Our findings highlight the need to continue exploring PrEP use and rising syphilis rates. In terms of policy, PrEP administration appears to be inversely associated with regions of greater social vulnerability. Further efforts should focus on the social determinants and health needs of this population to improve access to PrEP and reduce social disparities.

[Sexual violence against adolescents in Campo Grande, Mato Grosso do Sul, Brazil]. / Violência sexual contra adolescentes em Campo Grande, Mato Grosso do Sul.

OBJECTIVE: To analyze the situation of sexual violence against adolescents. METHODS: Cross-sectional study with spatial analysis, covering 172 reporting forms, from January 2009 to January 2013, in Campo Grande, Mato Grosso do Sul. Data were grouped by neighborhood for spatial analysis. The statistical analysis was descriptive. RESULTS: Adolescents in situations of violence were mostly girls (94.8%) and white (37.8%). Domestic violence prevailed (51.7%) and with one perpetrator (66.9%). Pregnancy (8.7%) was one of the consequences. The cases were evenly distributed in the city without a preferential spatial pattern and regardless of social background. CONCLUSIONS: Despite the underreporting of sexual violence cases, the frequency and the individual and collective consequences of this are serious enough to make it a public health issue.

Violência sexual contra adolescentes em Campo Grande, Mato Grosso do Sul / Violencia sexual contra adolescentes en Campo Grande, Mato Grosso do Sul, Brasil / Sexual violence against adolescents in Campo Grande, Mato Grosso do Sul, Brazil

RESUMO Objetivo Analisar a situação da violência sexual contra adolescentes. Métodos Estudo transversal com análise espacial, abrangendo 172 fichas de notificação, de janeiro de 2009 a janeiro de 2013, em Campo Grande, Mato Grosso do Sul. Para a análise espacial, os dados foram agrupados por bairro. A análise estatística dos dados foi descritiva. Resultados Os adolescentes em situação de violência foram majoritariamente meninas (94,8%) e de cor branca (37,8%). Predominou a violência intrafamiliar (51,7%) e com um perpetrador (66,9%). A gravidez (8,7%) foi uma das consequências. Os casos tiveram distribuição homogênea no município, sem padrão espacial preferencial e sem distinção de estrato social. Conclusões Apesar da subnotificação de casos de violência sexual, a frequência e as consequências individuais e coletivas desta são suficientemente graves para torná-la uma questão de saúde pública.

RESUMEN Objetivo Analizar la situación de la violencia sexual contra adolescentes. Métodos Estudio transversal mediante análisis espacial abarcando 172 fichas de notificación de enero de 2009 a enero de 2013, en la ciudad de Campo Grande, Mato Grosso do Sul, Brasil. Para el análisis espacial se reunieron los datos por barrios, con un análisis estadístico descriptivo. Resultados Los adolescentes en situación de violencia eran en su mayor parte muchachas (un 94,8%) y blancas (un 37,8%). Predominó la violencia intrafamiliar (un 51,7%) y con un perpetrador (un 66,9%). El embarazo (un 8,7%) fue una de las consecuencias. Los casos tuvieron distribución homogénea en el municipio, sin un patrón espacial de preferencia o distinciones por estrato social. Conclusión Pese a la subnotificación de episodios de violencia sexual, la frecuencia y las consecuencias individuales y colectivas son lo suficientemente graves como para transformarla en una cuestión de salud pública.

ABSTRACT Objective To analyze the situation of sexual violence against adolescents. Methods Cross-sectional study with spatial analysis, covering 172 reporting forms, from January 2009 to January 2013, in Campo Grande, Mato Grosso do Sul. Data were grouped by neighborhood for spatial analysis. The statistical analysis was descriptive. Results Adolescents in situations of violence were mostly girls (94.8%) and white (37.8%). Domestic violence prevailed (51.7%) and with one perpetrator (66.9%). Pregnancy (8.7%) was one of the consequences. The cases were evenly distributed in the city without a preferential spatial pattern and regardless of social background. Conclusions Despite the underreporting of sexual violence cases, the frequency and the individual and collective consequences of this are serious enough to make it a public health issue.

Gravidez na adolescência: estudo ecológico nas microrregiões de saúde do Estado do Mato Grosso do Sul, Brasil – 2008* / Adolescent pregnancy: an ecological study in the health micro-regions of the State of Mato Grosso do Sul, Brazil – 2008

Objetivo: descrever a proporção de nascidos vivos e a taxa de fecundidade de mães de 15 a 19 anos de idade e analisar sua correlação com indicadores socioeconômicos, nas microrregiões de saúde do estado de Mato Grosso do Sul, Brasil. Métodos: estudo ecológico com medidas agregadas por microrregião, calculadas a partir de (i) dados do Sistema de Informações sobre Nascidos Vivos (Sinasc) para o ano de 2008 e de (ii) indicadores de desenvolvimento social e econômico. Resultados: do total de 40.867 nascidos vivos, 22 por cento eram de mães adolescentes; as taxas específicas de fecundidade (15 a 19 anos) variaram de 73 a 116 por mil habitantes, entre as microrregiões de saúde estudadas; verificou-se correlação significativa entre taxas específicas de fecundidade e índice de responsabilidade social (r=0,646; p=0,032) e analfabetismo funcional (r=0,7180; p=0,013). Conclusão: a fecundidade das mulheres adolescentes tende a ser maior nas microrregiões com piores indicadores de escolaridade e desenvolvimento socioeconômico.

Objective: to describe the proportion of live births and the fertility rate of mothers aged 15-19 years and correlation with socio-economic indicators in the health micro-regions of Mato Grosso do Sul State. Methods: an ecological study using indicators aggregated by micro-region, calculated based on 2008 data from the Live Birth Information System and regional indicators of social and economic development. Results: teenage mothers accounted for 22 per cent of the total of 40,867 live births. Specific fertility rates (15-19 age group) ranged from 73 to 116 per thousand inhabitants in the health micro-regions studied. There was significant correlation between specific fertility rates and Social Responsibility Index (r = 0.646 p = 0.032) and functional illiteracy (r = 0.7180 p = 0.013). Conclusion: female adolescent fertility tends to be higher in micro-regions with the worst education and socio-economic development indicators.

Biotic factors and occurrence of Lutzomyia longipalpis in endemic area of visceral leishmaniasis, Mato Grosso do Sul, Brazil

The relationships between environmental exposure to risk agents and health conditions have been studied with the aid of remote sensing imagery, a tool particularly useful in the study of vegetation cover. This study aims to evaluate the influence of environmental variables on the spatial distribution of the abundance of Lutzomyia longipalpis and the reported canine and human visceral leishmaniasis (VL) cases at an urban area of Campo Grande, state of Mato Grosso do Sul. The sandfly captures were performed in 13 residences that were selected by raffle considering four residences or collection station for buffer. These buffers were generated from the central house with about 50, 100 and 200 m from it in an endemic area of VL. The abundance of sandflies and human and canine cases were georreferenced using the GIS software PCI Geomatica. The normalized difference vegetation index (NDVI) and percentage of land covered by vegetation were the environmental variables extracted from a remote sensing IKONOS-2 image. The average NDVI was considered as the complexity of habitat and the standard deviation as the heterogeneity of habitat. One thousand three hundred sixty-seven specimens were collected during the catch. We found a significant positive linear correlation between the abundance of sandflies and the percentage of vegetation cover and average NDVI. However, there was no significant association between habitat heterogeneity and the abundance of these flies.

Biotic factors and occurrence of Lutzomyia longipalpis in endemic area of visceral leishmaniasis, Mato Grosso do Sul, Brazil.

The relationships between environmental exposure to risk agents and health conditions have been studied with the aid of remote sensing imagery, a tool particularly useful in the study of vegetation cover. This study aims to evaluate the influence of environmental variables on the spatial distribution of the abundance of Lutzomyia longipalpis and the reported canine and human visceral leishmaniasis (VL) cases at an urban area of Campo Grande, state of Mato Grosso do Sul. The sandfly captures were performed in 13 residences that were selected by raffle considering four residences or collection station for buffer. These buffers were generated from the central house with about 50, 100 and 200 m from it in an endemic area of VL. The abundance of sandflies and human and canine cases were georreferenced using the GIS software PCI Geomatica. The normalized difference vegetation index (NDVI) and percentage of land covered by vegetation were the environmental variables extracted from a remote sensing IKONOS-2 image. The average NDVI was considered as the complexity of habitat and the standard deviation as the heterogeneity of habitat. One thousand three hundred sixty-seven specimens were collected during the catch. We found a significant positive linear correlation between the abundance of sandflies and the percentage of vegetation cover and average NDVI. However, there was no significant association between habitat heterogeneity and the abundance of these flies.